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Friday, February 21, 2020

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The deadly polio virus may be the key to curing some cancers. By injecting a genetically engineered, modified version of the Poliovirus  in two patients with glioblastoma brain tumors, a doctor has eliminated their tumors without infecting them with polio.

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CBS's "60 Minutes" followed the patients for 10 months during the trial and will release the full report Sunday. Matthias Gromeier, a molecular biologist at Duke University, has been researching the idea for 15 years, first beginning with studies, then animal trials and now human tests.

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Boil them, deep-freeze them, crush them, dry them out or blast them into space: tardigrades will survive it all and come back for more. If you go into outer space without protection, you'll die.

Tardigrades_Tiny_Animals

Tardigardes are about 1mm Long

The lack of pressure would force the air in your lungs to rush out. Gases dissolved in your body fluids would expand, pushing the skin apart and forcing it to inflate like a balloon. Your eardrums and capillaries would rupture, and your blood would start to bubble and boil. Even if you survived all that, ionising radiation would rip apart the DNA in your cells. Mercifully, you would be unconscious in 15 seconds.

 

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Cambridge University has achieved a new stem cell research that could allow the first fully "manufactured" baby to be created from the skin cells of two adults of the same gender, opening the door to same-sex couples having their own biological babies.

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Researchers from Cambridge University working together with Israel's Weizmann Institute of Science, have paired stem cell lines from embryos with the skin of five different adults, according to the study published in the journal Cell.  The medical experiment had previously succeeded in creating live baby mice, but this is the first study on humans in which the engineered cells created in the laboratory were compared to aborted fetuses to determine an identical match.

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In a remarkable new advance against the virus that causes AIDS, scientists from the Scripps Research Institiute in Jupiter, Florida have announced the creation of a novel drug candidate that is so potent and universally effective, it might work as part of an unconventional vaccine.

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Scanning Electron Micrograph of HIV

Particles Infecting a Human T Cell 

The research, which involved scientists from more than a dozen research institutions, was published February 18, 2015 online ahead of print by the journal Nature.  The study shows that the new drug candidate blocks every strain of HIV-1, HIV-2 and SIV (simian immunodeficiency virus) that has been isolated from humans or rhesus macaques, including the hardest-to-stop variants. It also protects against much-higher doses of virus than occur in most human transmission and does so for at least eight months after injection.

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The World Health Organization(WHO) is to "ramp up" efforts to prevent Ebola spreading beyond the three countries most affected by the deadly virus. Fifteen African countries are being prioritized, top WHO official Isabelle Nuttall told a Geneva news conference. They will receive more help in areas including prevention and protection.

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The transmission of the Ebola virus remains intense in Liberia, Sierra Leone and Guinea, the WHO's Dr Nuttall said. There was a "spike" in the Guinean capital, Conakry, said Dr Nuttall, and "intense transmission" in Freetown, the capital of Sierra Leone. In the Liberian capital, Monrovia, she spoke of "significant underreporting" and problems with data-gathering making it hard to reach firm conclusions. But there was a drop in the number of cases in Lofa district.